KEGG   Homo sapiens (human): 9175
Entry
9175              CDS       T01001                                 
Symbol
MAP3K13, LZK, MEKK13, MLK
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 13
  KO
K04422  mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Network
nt06526  MAPK signaling
  Element
N01594  MLK-JNK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    9175 (MAP3K13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9175 (MAP3K13)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     9175 (MAP3K13)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: TKL group
  MLK family
   9175 (MAP3K13)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 9175
NCBI-ProteinID: NP_001229243
OMIM: 604915
HGNC: 6852
Ensembl: ENSG00000073803
UniProt: O43283
Position
3:185282961..185489094
AA seq 966 aa
MANFQEHLSCSSSPHLPFSESKTFNGLQDELTAMGNHPSPKLLEDQQEKGMVRTELIESV
HSPVTTTVLTSVSEDSRDQFENSVLQLREHDESETAVSQGNSNTVDGESTSGTEDIKIQF
SRSGSGSGGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQG
AVFLGKFRAEEVAIKKVREQNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQ
LYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGT
SKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSA
IIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQE
TYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERAN
NLYMELSAIMLQLEMREKELIKREQAVEKKYPGTYKRHPVRPIIHPNAMEKLMKRKGVPH
KSGMQTKRPDLLRSEGIPTTEVAPTASPLSGSPKMSTSSSKSRYRSKPRHRRGNSRGSHS
DFAAILKNQPAQENSPHPTYLHQAQSQYPSLHHHNSLQQQYQQPPPAMSQSHHPRLNMHG
QDIATCANNLRYFGPAAALRSPLSNHAQRQLPGSSPDLISTAMAADCWRSSEPDKGQAGP
WGCCQADAYDPCLQCRPEQYGSLDIPSAEPVGRSPDLSKSPAHNPLLENAQSSEKTEENE
FSGCRSESSLGTSHLGTPPALPRKTRPLQKSGDDSSEEEEGEVDSEVEFPRRQRPHRCIS
SCQSYSTFSSENFSVSDGEEGNTSDHSNSPDELADKLEDRLAEKLDDLLSQTPEIPIDIS
SHSDGLSDKECAVRRVKTQMSLGKLCVEERGYENPMQFEESDCDSSDGECSDATVRTNKH
YSSATW
NT seq 2901 nt   +upstreamnt  +downstreamnt
atggccaactttcaggagcacctgagctgctcctcttctccacacttacccttcagtgaa
agcaaaaccttcaatggactacaagatgagctcacagctatggggaaccacccttctccc
aagctgctcgaggaccagcaggaaaaggggatggtacgaacagagctaatcgagagcgtg
cacagccccgtcaccacaacagtgttgacgagcgtaagtgaggattccagggaccagttt
gagaacagcgttcttcagctaagggaacacgatgaatcagagacggcggtgtctcagggg
aacagcaacacggtggacggagagagcacaagcggaactgaagacataaagattcagttc
agcaggtcaggcagtggcagtggtgggtttcttgaaggactatttggatgcttaaggcct
gtatggaatatcattgggaaggcatattccactgattacaaattgcagcagcaagatact
tgggaagtgccatttgaggagatctcagagctgcagtggctgggtagtggagcccaagga
gcggtcttcttgggcaagttccgggcggaagaggtggccatcaagaaagtgagagaacag
aatgagacggatatcaagcatttgaggaagttgaagcaccctaacatcatcgcattcaag
ggtgtttgtactcaggccccatgttattgtattatcatggaatactgtgcccatggacaa
ctctacgaggtcttacgagctggcaggaagatcacacctcgattgctagtagactggtcc
acaggaattgcaagtggaatgaattatttgcacctccataaaattattcatcgtgatctc
aaatcacctaatgttttagtgacccacacagatgcggtaaaaatttcagattttggtaca
tctaaggaactcagtgacaaaagtaccaagatgtcatttgctggcacggtcgcatggatg
gcgccagaggtgatacggaatgaacctgtctctgaaaaagttgatatatggtcttttgga
gtggtgctttgggagctgctgacaggagagatcccttacaaagatgtagattcttcagcc
attatctggggtgttggaagcaacagcctccaccttccagttccttccacttgccctgat
ggattcaaaatccttatgaaacagacgtggcagagtaaacctcgaaaccgaccttctttt
cggcagacactcatgcatttagacattgcctctgcagatgtacttgccaccccacaagaa
acttacttcaagtctcaggctgaatggagagaagaagtgaaaaaacattttgagaagatc
aaaagtgaaggaacttgtatacaccggttagatgaagaactgattcgaaggcgcagagaa
gagctcaggcatgcgctggatattcgtgaacactatgagcggaagcttgagcgggcgaat
aatttatacatggaattgagtgccatcatgctgcagctagaaatgcgggagaaggagctc
attaagcgtgagcaagcagtggaaaagaagtatcctgggacctacaaacgacaccctgtt
cgtcctatcatccatcccaatgccatggagaaactcatgaaaaggaaaggagtgcctcac
aaatctgggatgcagaccaaacggccagacttgttgagatcagaagggatccccaccaca
gaagtggctcccactgcatcccctttgtccggaagtcccaaaatgtccacttctagcagc
aagagccgatatcgaagcaaaccacgccaccgccgagggaatagcagaggcagccatagt
gactttgccgcaatcttgaaaaaccagccagcccaggaaaattcaccccatcccacttac
ctgcaccaagctcaatcccaatacccttctcttcatcaccataattctctgcagcagcaa
taccagcagccccctcctgccatgtcccagagtcaccatcccagactcaatatgcacgga
caggacatagcaacctgcgccaacaacctgaggtatttcggcccagcagcagccctgcgg
agcccactcagcaaccatgctcagagacagctgcccggctcgagccctgacctcatctcc
acagccatggctgcagactgctggagaagttctgagcctgacaagggccaagctggtccc
tggggctgttgccaggctgacgcttatgacccctgccttcagtgcaggccagaacagtat
gggtccttagacataccctctgctgagccagtggggaggagccctgacctttccaagtca
ccagcacataatcctctcttggaaaacgcccagagttctgagaaaacggaagaaaatgaa
ttcagcggctgtaggtctgagtcatccctcggcacctctcatctcggcacccctccagcg
ctacctcgaaaaacaaggcctctgcagaagagtggagatgactcctcagaagaggaagaa
ggggaagtagatagtgaagttgaatttccacgaagacagaggccccatcgctgtatcagc
agctgccagtcatattcaacctttagctctgagaatttctctgtgtctgatggagaagag
ggaaataccagtgaccactcaaacagtcctgatgagttagctgataaacttgaagaccgc
ttggcagagaagctagacgacctgctgtcccagacgccagagattcccattgacatatcc
tcacactcggatgggctctctgacaaggagtgtgccgtgcgccgtgtgaagactcagatg
tctctgggcaagctgtgtgtggaggaacgtggctatgagaaccccatgcagtttgaagaa
tcggactgtgactcttcagatggggagtgttctgatgccacagttaggaccaataaacac
tacagctctgctacctggtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (40)   
   RefSeq(nuc) (12)   
   GenBank (14)   
   EMBL (14)   
Protein domain (4)   
   Pfam (4)   
All databases (84)   

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